ACCUFINE 10MG contains Isotretinoin which belongs to a group of medicines known as retinoids which is used to treat skin problems. Isotretinoin used to treat severe nodular acne. It is only used in patients whose acne has not responded to other treatments. It works by shrinking the oil, sebaceous, glands in the skin. This reduces the amount of oil that is produced naturally by skin and also kills the bacteria that cause acne and relieves redness and soreness.